The Big Bang Theory, Seasons 1-11

Worlds, atoms and neighbors collide in Seasons One through Eleven of The Big Bang Theory. Leonard and Sheldon are geniuses in the laboratory, but awkward most everywhere else. Enter beautiful, street-smart Penny, who aims to teach them a thing or two about life. Despite their on-again, off-again history, Leonard and Penny finally get hitched. Even Sheldon finds a female companion, entering into a “Relationship Agreement” with neurobiologist Amy Farrah Fowler, and ultimately proposing marriage. In their free time, Leonard and Sheldon enjoy fantasy role-playing games with their ever-expanding universe of friends, including fellow scientists Raj and Howard, and Howard's adorable microbiologist wife, Bernadette, who’s adjusting to life with their expanding family.